Angiotensin receptor blockers (ARBs)



ATC CODE

  • C09CA

INDICATION AND NEMLC RECOMMENDATIONS

INDICATION AND NEMLC RECOMMENDATION 1

INDICATION

  • Add on therapy in cardiac failure on patients already on standard treatment including ACE-inhibitors, ß-Blockers and spironolactone.

RECOMMENDATION

  • Not Approved

REVIEW INDICATORS

  • New efficacy data from large RCT indicating larger benefit of adding ARBs to standard therapy
  • Decrease in price of ARBs so as to be similarly priced to ACE-inhibitors

DATE RATIFIED

  • 20 September 2007



INDICATION AND NEMLC RECOMMENDATION 2

INDICATION

  • As add on therapy in proteinuric nephropathies in patients already using an ACE-inhibitor.

RECOMMENDATION

  • Not Approved
    Insufficient evidence to support its use.

REVIEW INDICATORS

  • New evidence indicating benefit in the form of a RCT of sufficient size with maximal doses of ACE-inhibitor used.
  • New safety concerns.
  • Decrease in price so as to be similarly priced to ACE-inhibitors.

DATE RATIFIED

  • 20 September 2007