Linezolid

• ATC Code
• Indication
• NEMLC Recommendation
• Review Indicators
• Date Ratified

ATC CODE

• J01XX08

INDICATION

• Resistant gram positive infections where vancomycin is contra-indicated.

NEMLC RECOMMENDATION

• Approved – Special Access
  It may be available on special access basis as approved by PTC for:
  • Only with a microbiology report confirming vancomycin resistance in a relative organism or confirmation of severe adverse effect to vancomycin, (i.e. vancomycin induced neutropenia or anaphylaxis, but not the “red man syndrome”).
  • confirmed contra-indication to the use of vancomycin.

REVIEW INDICATORS

• Clinically significant increase in vancomycin resistance in the public sector.
• Significant decrease in cost of linezolid.

DATE RATIFIED

• 27 November 2008