Intravenous Immunoglobulin (IVIG)

ATC CODE

  • J06BA02

INDICATIONS AND NEMLC RECOMMENDATIONS

INDICATIONS AND NEMLC RECOMMENDATIONS 1

  • Acute Immune thrombocytopenic Purpura (ITP)

NEMLC RECOMMENDATION

  • Approved
    • Life-threatening bleed with platelets <50 x 10⁹/l.
    • Urgent surgery (any surgery urgently required within 24 hours) where rapid rise in platelets is required.
    • Pregnant patient prior to delivery as above.
    • Rapid rise in platelets required when a patient has platelet count of < 20 x 10⁹/L, with additional risk factors for bleeding (such as severe hypertension, ongoing sepsis).

REVIEW INDICATORS

  • Evidence of harm

DATE RATIFIED

  • 5 July 2018

INDICATIONS AND NEMLC RECOMMENDATIONS 2

  • Primary antibody immune deficiency with recurrent infections

NEMLC RECOMMENDATION

  • Approved

REVIEW INDICATORS

  • New data on dosing
  • Availability of more affordable subcutaneous formulations

DATE RATIFIED

  • 11 April 2019

INDICATIONS AND NEMLC RECOMMENDATIONS 3

  • Guillain-Barré syndrome (GBS) presenting within the first 2 weeks of onset of moderate to severe weakness.

NEMLC RECOMMENDATION

  • Approved
    • The recommended regimen is 0.4 g/kg daily for 5 days.

REVIEW INDICATORS

  • New evidence

DATE RATIFIED

  • 5 December 2019