Echinocandins (caspofungin micafungin anidulafungin)


ATC CODE

  • J02AX04/J02AX05/J02AX06

INDICATION

  • Invasive candidiasis (resistant to fluconazole/amphotericin B and/or where renal dysfunction is present and amphotericin B cannot be used).

NEMLC RECOMMENDATION

  • Approved – Special Access
    • Echinocandins approved as a class, with the most affordable agent to be procured.
    • The use of echinocandins should be managed through motivation/ appropriate restrictions at facilities, as part of Antimicrobial Stewardship activities. (See addendum – clinical criteria for use)

REVIEW INDICATORS

  • Availability of amphotericin B
  • Changing resistance patterns
  • New evidence

DATE RATIFIED

  • 12 April 2018