A15.0-3/A15.7-8/A16.0-2/A16.3-4/A16.7-89/B20.0 + (U50.00-01/U50.10-11)
MEDICINE TREATMENT
Confirmed INH mono-resistant TB:
- Rifampicin, oral, 10 mg/kg daily.
AND
- Ethambutol, oral, 15 mg/kg daily.
AND
- Pyrazinamide, oral, 25 mg/kg daily.
AND
- Levofloxacin, oral, daily.
LoE:III [46]
Where single medicines are not available or the pill burden is too high a FDC of RHZE dosed as per weight may be used, and levofloxacin added to this.
Treatment should be given for at least 6 months.