| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[6] Amoxicillin/clavulanic acid – Children ≤ 35 kg: Bosch FJ, van Vuuren C, Joubert G. Antimicrobial resistance patterns in outpatient urinary tract infections--the constant need to revise prescribing habits. S Afr Med J. 2011 May;101(5):328-31. http://www.ncbi.nlm.nih.gov/pubmed/21837876
Amoxicillin/clavulanic acid – Children ≤ 35 kg: Zorc JJ, Kiddoo DA, Shaw KN. Diagnosis and management of pediatric urinary tract infections. ClinMicrobiol Rev. 2005 Apr;18(2):417-22. http://www.ncbi.nlm.nih.gov/pubmed/15831830
Amoxicillin/clavulanic acid – Children ≤ 35 kg: Bamford C, Bonorchis K, Ryan A, Hoffmann R, Naicker P, Maloba M, Nana T, Zietsman I, Govind C. Antimicrobial susceptibility patterns of Escherichia coli strains isolated from urine samples in South Africa from 2007-2011. South Afr J Epidemiol Infect 2012;27(2):46-52. http://www.sajei.co.za/index.php/SAJEI/article/view/483
Amoxicillin/clavulanic acid – Children ≤ 35 kg: Lewis DA, Gumede LY, van der Hoven LA, de Gita GN, de Kock EJ, de Lange T, Maseko V, Kekana V, Smuts FP, Perovic O. Antimicrobial susceptibility of organisms causing community-acquired urinary tract infections in Gauteng Province, South Africa. S Afr Med J. 2013 Mar 15;103(6):377-81. http://www.ncbi.nlm.nih.gov/pubmed/23725955
Amoxicillin/clavulanic acid – Children ≤ 35 kg: Fitzgerald A, Mori R, Lakhanpaul M, Tullus K. Antibiotics for treating lower urinary tract infection in children. Cochrane Database Syst Rev. 2012 Aug 15;8:CD006857. http://www.ncbi.nlm.nih.gov/pubmed/22895956
Amoxicillin/clavulanic acid – Children ≤ 35 kg: Keren R, Chan E. A meta-analysis of randomized, controlled trials comparing short- and long-course antibiotic therapy for urinary tract infections in children. Pediatrics. 2002 May;109(5):E70-0. http://www.ncbi.nlm.nih.gov/pubmed/11986476
Amoxicillin/clavulanic acid – Children ≤ 35 kg: Downs SM. Technical report: urinary tract infections in febrile infants and young children. The Urinary Tract Subcommittee of the American Academy of Pediatrics Committee on Quality Improvement. Pediatrics. 1999 Apr;103(4):e54. http://www.ncbi.nlm.nih.gov/pubmed/10103346
Amoxicillin/clavulanic acid – Children ≤ 35 kg: American Academy of Pediatrics. Committee on Quality Improvement. Subcommittee on Urinary Tract Infection. Pediatrics. 1999 Apr;103(4 Pt 1):843-52. Erratum in: Pediatrics1999 May;103(5 Pt 1):1052, 1999 Jul;104(1 Pt 1):118. 2000 Jan;105(1 Pt 1):141. http://www.ncbi.nlm.nih.gov/pubmed/10103321
Amoxicillin/clavulanic acid – Children ≤ 35 kg: Kennedy KM, Glynn LG, Dineen B. A survey of the management of urinary tract infection in children in primary care and comparison with the NICE guidelines. BMC Fam Pract. 2010 Jan 26;11:6. http://www.ncbi.nlm.nih.gov/pubmed/20102638
Amoxicillin/clavulanic acid – Children ≤ 35 kg: Shann F. Drug doses, 15th edition, 2010. Intensive Care Unit,Royal Children’s Hospital, Parkville, Victoria 3052, Australia.
Amoxicillin/clavulanic acid – Children ≤ 35 kg: Triomed, RSA. Package insert for Augmaxcil®S, SF (Powder for suspension, suspension forte). 1997.
Amoxicillin/clavulanic acid – Children ≤ 35 kg: Montini G, Toffolo A, Zucchetta P, Dall'Amico R, Gobber D, Calderan A, Maschio F, Pavanello L, Molinari PP, Scorrano D, Zanchetta S, Cassar W, Brisotto P, Corsini A, Sartori S, Da Dalt L, Murer L, Zacchello G. Antibiotic treatment for pyelonephritis in children: multicentre randomised controlled non-inferiority trial. BMJ. 2007 Aug 25;335(7616):386. http://www.ncbi.nlm.nih.gov/pubmed/17611232