| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[18] Midazolam, IM (adults-status epilepticus):Silbergleit R, Durkalski V,Lowenstein D,Conwit R,Pancioli A,Palesch Y,Barsan W; NETT Investigators. Intramuscular versus intravenous therapy for prehospital status epilepticus. NEnglJMed. 2012Feb16; 366(7):591-600. http://www.ncbi.nlm.nih.gov/pubmed/22335736