| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[8] Isosorbide mononitrate, oral:: National Department of Health: Essential Drugs Programme. Adult Hospital level STGs and EML, 2019. http://www.health.gov.za/
Isosorbide mononitrate, oral:: Thadani U, Lipicky RJ. Short and long-acting oral nitrates for stable angina pectoris. Cardiovasc Drugs Ther. 1994 Aug;8(4):611-23. https://www.ncbi.nlm.nih.gov/pubmed/7848896
Isosorbide mononitrate, oral:: Parker JO. Eccentric dosing with isosorbide-5-mononitrate in angina pectoris. Am J Cardiol. 1993 Oct 15;72(12):871-6. https://www.ncbi.nlm.nih.gov/pubmed/8213541
Isosorbide mononitrate, oral:: South African Medicines Formulary. 12th Edition. Division of Clinical Pharmacology. University of Cape Town. 2016.