| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
|---|---|---|
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
2 Dexamethasone: Odio CM, et. al. Double blind, randomized, placebo-controlled study of dexamethasone therapy for hematogenous septic arthritis in children. Pediatr Infect Dis J. 2003, 22:883-886; Harel L, et. al. Dexamethasone therapy for septic arthritis in children. J Pediatr Orthop. 2011; 31:211-215.