| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[11] Ertapenem, IV (severe penicillin allergy & confirmed Gram negative culture): An MM, Zou Z, Shen H, Zhang JD, Chen ML, Liu P, Wang R, Jiang YY. Ertapenem versus piperacillin/tazobactam for the treatment of complicated infections: a meta-analysis of randomized controlled trials. BMC Infect Dis. 2009 Dec 2;9:193. https://www.ncbi.nlm.nih.gov/pubmed/19951447
Ertapenem (severe penicillin allergy & confirmed Gram negative culture): NICD AMR surveillance for ESKAPE, 1 January 2016 to 31 December 2016.