Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[7] Polyvalent antivenom (neurotoxic, cytotoxic or unidentified snakebites): Müller GJ, Modler H, Wium CA, Veale DJH, Marks CJ. Snake bite in southern Africa: diagnosis and management. CME Oct 2012; 30(10):362-82.http://www.cmej.org.za/index.php/cmej/article/view/2546/2581
Polyvalent antivenom: South African Medicines Formulary. 12th Edition. Division of Clinical Pharmacology. University of Cape Town, 2016.