Cotrimoxazole poisoning

T37.0


DESCRIPTION

In acute overdose, low toxicity expected. Symptoms include nausea and vomiting, dizziness, headache and neurological symptoms (such as drowsiness, confusion and mental depression). Other signs include bone marrow depression, haematuria and renal insufficiency. Hypersensitivity reactions may occur.

GENERAL MEASURES

Treatment is symptomatic and supportive.

Monitor FBC, electrolytes, glucose, hepatic and renal function in symptomatic patients.