| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[19] ART regimens (pregnancy): South African National Department of Health South Africa. Guideline for the Prevention of Mother to Child Transmission of Communicable Infections, October 2019. https://www.knowledgehub.org.za/elibrary/guideline-prevention-mother-child-transmission-communicable-infections