Reference 60

Level I Good quality evidence Systematic review of RCTs with consistent findings
High quality individual RCT
Level II Limited quality patient orientated evidence Systematic review of lower quality studies or studies with inconsistent findings
Low quality clinical trial
Cohort studies
Case-control studies
Level III Other Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series

[60] Amphotericin B: Southern African HIV Clinicians Society: Guideline for the prevention, diagnosis and management of cryptococcal meningitis among HIV-infected persons:2013 update. S Afr J HIV Med 2013;14(2):76-86. [Online][Accessed 8March2015] http://www.sajhivmed.org.za/index.php/hivmed/article/view/82

Fluconazole: Southern African HIV Clinicians Society: Guideline for the prevention, diagnosis and management of cryptococcal meningitis among HIV-infected persons:2013 update. S Afr J HIV Med 2013;14(2):76-86. [Online][Accessed 8March2015] http://www.sajhivmed.org.za/index.php/hivmed/article/view/82