| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II | Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other | Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
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Status epilepticus, initial treatment algorithm: National Institute for Health and Care Excellence. Epilepsies: diagnosis and management: Clinical guideline. 2012; Jan https://wwwnice.org.uk/guidance/cg137
Status epilepticus, initial treatment algorithm (therapeutic drug monitoring): Nikooie R, Neufeld KJ, Oh ES, Wilson LM, Zhang A, Robinson KA, Needham DM. Antipsychotics for Treating Delirium in Hospitalized Adults: A Systematic Review. Ann Intern Med. 2019 Sep 3. https://www.ncbi.nlm.nih.gov/pubmed/31476770