| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[11] Early BP Lowering (within 7 days of stroke onset): Wang H, Tang Y, Rong X, Li H, Pan R, Wang Y, Peng Y. Effects of early blood pressure lowering on early and long-term outcomes after acute stroke: an updated meta-analysis. PLoS One. 2014 May 22;9(5):e97917. https://www.ncbi.nlm.nih.gov/pubmed/24853087