Nephrotic syndrome

N04.9


DESCRIPTION

Glomerular disease characterised by:

  • severe proteinuria, i.e.: PCR >0.25 g/mmol

and

  • oedema,
  • hypoalbuminaemia, and
  • hyperlipidaemia.

The cause cannot be determined accurately without a biopsy.

GENERAL MEASURES

Regulate salt and fluid intake.

Weigh regularly to assess fluid retention.

Check for postural hypotension to identify excessive diuresis.

Evaluate proteinuria with PCR:

  • initially – weekly
  • when discharged – monthly, until stable

Monitor potassium frequently for patients on ACE-inhibitors and/or diuretics.

MEDICINE TREATMENT

Management should be guided by a specialist.

CONSULTATION/REFERRAL

All patients.