Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[9] Clindamycin, oral dose: Bouazza N, Pestre V, Jullien V, Curis E, Urien S, Salmon D, Tréluyer JM. Population pharmacokinetics of clindamycin orally and intravenously administered in patients with osteomyelitis. Br J Clin Pharmacol. 2012 Dec;74(6):971-7. http://www.ncbi.nlm.nih.gov/pubmed/22486719
Clindamycin, oral dose: Wasserman et al. South African antibiotic stewardship programme (SAASP): A pocket guide to antibiotic prescribing for adults in South Africa, 2014. http://www.fidssa.co.za/images/SAASP_Antibiotic_Gudidelines_2015.pdf