Candidiasis of oesophagus/trachea/bronchi

B20.4


DESCRIPTION

Mucosal candidiasis involving the oesophagus/trachea/bronchi is AIDS-defining (WHO clinical stage 4). Oesophagitis is by far the commonest manifestation.

Clinical features: symptoms of pain or difficulty on swallowing. Oral thrush is present in most patients.

GENERAL MEASURES

Maintain adequate hydration.

MEDICINE TREATMENT

  • Fluconazole, IV/oral, 200 mg daily for 14 days.
    • The usual route is oral but give IV if patient unable to swallow or is vomiting.
    • An early relapse should be treated with a 4-week course of fluconazole as above.

Note: Primary or secondary fluconazole prophylaxis for mucosal candidiasis is not recommended.