Reference 26

Level I Good quality evidence Systematic review of RCTs with
consistent findings
High quality individual RCT
Level II Limited quality patient
orientated evidence
Systematic review of lower quality
studies or studies with inconsistent
findings
Low quality clinical trial
Cohort studies
Case-control studies
Level III Other Consensus guidelines, extrapolations
from bench research, usual practice,
opinion, disease-oriented evidence
(intermediate or physiologic outcomes
only), or case series

[26] Mifepristone, oral (TOP - 2nd trimester): Wildschut H, Both MI, Medema S, Thomee E, Wildhagen MF, Kapp N. Medical methods for mid-trimester termination of pregnancy. Cochrane Database Syst Rev. 2011 Jan 19;(1):CD005216. https://www.ncbi.nlm.nih.gov/pubmed/21249669

Mifepristone, oral (TOP - 2nd trimester): National Department of Health: Affordable Medicines, EDP-Adult Hospital level. Medicine Review Update: Mifepristone for medical termination of pregnancy, 20 October 2017. http://www.health.gov.za/

Mifepristone, oral (TOP – 2nd trimester): The Royal College of Obstetricians and Gynaecologist. Best practice in comprehensive abortion care, June 2015. https://www.rcog.org.uk/globalassets/documents/guidelines/best-practice-papers/best-practice-paper-2.pdf