Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[26] Mifepristone, oral (TOP - 2nd trimester): Wildschut H, Both MI, Medema S, Thomee E, Wildhagen MF, Kapp N. Medical methods for mid-trimester termination of pregnancy. Cochrane Database Syst Rev. 2011 Jan 19;(1):CD005216. https://www.ncbi.nlm.nih.gov/pubmed/21249669
Mifepristone, oral (TOP - 2nd trimester): National Department of Health: Affordable Medicines, EDP-Adult Hospital level. Medicine Review Update: Mifepristone for medical termination of pregnancy, 20 October 2017. http://www.health.gov.za/
Mifepristone, oral (TOP – 2nd trimester): The Royal College of Obstetricians and Gynaecologist. Best practice in comprehensive abortion care, June 2015. https://www.rcog.org.uk/globalassets/documents/guidelines/best-practice-papers/best-practice-paper-2.pdf