| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[2] Fluoroquinolone ophthalmic drops: Sheikh A, Hurwitz B, van Schayck CP, McLean S, Nurmatov U. Antibiotics versus placebo for acute bacterial conjunctivitis. Cochrane Database Syst Rev. 2012 Sep 12;(9):CD001211. https://www.ncbi.nlm.nih.gov/pubmed/22972049
Fluoroquinolone ophthalmic drops: Epling J. Bacterial conjunctivitis. BMJ Clin Evid. 2012 Feb 20;2012. pii: 0704. https://www.ncbi.nlm.nih.gov/pubmed/22348418
Fluoroquinolone ophthalmic drops: Silver LH, Woodside AM, Montgomery DB. Clinical safety of moxifloxacin ophthalmic solution 0.5% (VIGAMOX) in pediatric and nonpediatric patients with bacterial conjunctivitis. Surv Ophthalmol. 2005 Nov;50 Suppl 1:S55-63. https://www.ncbi.nlm.nih.gov/pubmed/16257311
Fluoroquinolone ophthalmic drops (ciprofloxacin ophthalmic drops - dosing): South African Medicines Formulary. 12th Edition. Division of Clinical Pharmacology. University of Cape Town, 2016.
Fluoroquinolone ophthalmic drops (ciprofloxacin ophthalmic drops - dosing): Leibowitz HM. Antibacterial effectiveness of ciprofloxacin 0.3% ophthalmic solution in the treatment of bacterial conjunctivitis. Am J Ophthalmol. 1991 Oct;112(4 Suppl):29S-33S. https://www.ncbi.nlm.nih.gov/pubmed/1928271