S05.6 + (Y43.99)
DESCRIPTION
Infection of the ocular cavity is an emergency as it can cause blindness. This may occur secondary to bacteraemia (endogenous infection) or, more commonly, after penetrating ocular injury or surgery.
In patients with endogenous endophthalmitis blood cultures should be done and the source of infection identified and treated.
In patients with endophthalmitis after penetrating injury/surgery culture should be done on specimens of aqueous or vitreous humour..
MEDICINE TREATMENT
Refer immediately to an ophthalmologist.
Endogenous endophthalmitis
Specialist initiated, vitrectomy often required:
- Ceftriaxone, IV, 2 g daily for 7 days.
Adjust antibiotics according to culture and sensitivity results
AND
- Ceftazidime, intravitreal, 2.25 mg.
AND
- Vancomycin, intravitreal, 1 mg.
Administer using separate tuberculin syringes.
Post-surgical endophthalmitis
Specialist initiated, vitrectomy often required:
- Ceftazidime, intravitreal, 2.25 mg.
AND
- Vancomycin, intravitreal, 1 mg.
Administer using separate tuberculin syringes.
In addition, if there is soft tissue involvement or as prophylaxis after a penetrating eye injury:
- Ciprofloxacin, oral, 750 mg 12 hourly for 7 days.