| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[15] Podophyllotoxin 0.5%, topical: National Department of Health: Affordable Medicines, EDP-Adult Hospital level. Medicine Review: Ano-genital warts, May 2018. http://www.health.gov.za/
Podophyllotoxin 0.5%, topical: Thurgar E, Barton S, Karner C, Edwards SJ. Clinical effectiveness and cost-effectiveness of interventions for the treatment of anogenital warts: systematic review and economic evaluation. Health Technol Assess. 2016 Mar;20(24):v-vi, 1-486. https://www.ncbi.nlm.nih.gov/pubmed/27034016
Podophyllin 20% in compound tincture benzoin BP, topical: Thurgar E, Barton S, Karner C, Edwards SJ. Clinical effectiveness and cost-effectiveness of interventions for the treatment of anogenital warts: systematic review and economic evaluation. Health Technol Assess. 2016 Mar;20(24):v-vi, 1-486. https://www.ncbi.nlm.nih.gov/pubmed/27034016