Prednisone tapering - generally required after prolonged use (i.e. >1 week)
Example of a dose reduction regimen: for an initial dose of 60 mg daily, reduce initial dose by 2/3, and continue as follows:
- 40 mg/day in week 2,
- 25 mg/day in week 3,
- 20 mg/day in week 4,
- 15 mg/day in week 5,
- 10 mg /day in week 6 and
- thereafter 5 mg daily for 1 week and then discontinue.
Note: Weaning should be adjusted according to clinical context. If control deteriorates on weaning return to the previous effective dose.