- Digoxin, oral, 0.125 mg daily, adjust according to rate response, if in atrial fibrillation, and trough plasma level.
- Digoxin trough plasma levels (before the morning dose) should be maintained between 0.6–1 nmol/L. Monitor after 7 days and periodically thereafter.
- Patients at high risk of digoxin toxicity are:
- the elderly,
- patients with renal dysfunction,
- hypokalaemia, and
- patients with low lean body mass.