| Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
| Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
| Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[23] Ciprofloxacin, oral (extended course for cholera): National Institute for Communicable Diseases. Data on file, 2020.
Ciprofloxacin, oral (extended course for cholera): Communicable Diseases Communiqué, January 2020, Vol. 19 (1). http://www.nicd.ac.za/