Level I | Good quality evidence |
Systematic review of RCTs with consistent findings High quality individual RCT |
Level II |
Limited quality patient orientated evidence |
Systematic review of lower quality studies or studies with inconsistent findings Low quality clinical trial Cohort studies Case-control studies |
Level III | Other |
Consensus guidelines, extrapolations from bench research, usual practice, opinion, disease-oriented evidence (intermediate or physiologic outcomes only), or case series |
[10] Azithromycin: Dong J, Yu XF, Zou J. Azithromycin-containing versus standard triple therapy for Helicobacter pylori eradication: a meta-analysis. World J Gastroenterol. 2009 Dec 28;15(48):6102-10. http://www.ncbi.nlm.nih.gov/pubmed/20027685
Azithromycin: National Department of Health. Essential Drugs Programme. Medicine review: The efficacy of Azithromycin compared to Clarithromycin in the treatment of H.Pylori infection, 26 November 2015. http://health.gov.za/
Azithromycin: Sampson MR, Dumitrescu TP, Brouwer KL, Schmith VD. Population pharmacokinetics of azithromycin in whole blood, peripheral blood mononuclear cells, and polymorphonuclear cells in healthy adults. CPT Pharmacometrics Syst Pharmacol. 2014;3(3):e103. https://pubmed.ncbi.nlm.nih.gov/24599342/
Azithromycin: Amsden GW, Gray CL. Serum and WBC pharmacokinetics of 1500 mg of azithromycin when given either as a single dose or over a 3 day period in healthy volunteers. J Antimicrob Chemother. 2001;47(1):61-66. https://pubmed.ncbi.nlm.nih.gov/11152432/